Engineering cures for autoimmune diseases.
Our Approach
We combine cutting-edge genetic engineering and deep immunology expertise to pioneer scalable curative therapies for inflammation and autoimmunity.
How it works
Therapies to restore homeostasis
Our novel regulatory T cell-based therapeutics mimic the function of naturally occurring Type 1 regulatory T (Tr1) cells. Designed to restore immune tolerance, our therapies aim to stop severe autoimmune and inflammatory diseases in their tracks.
Program Highlights
Targeted immune modulation, at scale
Our cells produce suppressive cytokines directly within inflamed tissues while preserving healthy immune responses.
Engineered for durability, our cells remain stable and functional even in inflammatory environments.
Our therapies migrate to sites of inflammation, modulate effector responses, and drive formation of new Tr1 cells.
Our Therapeutic Programs
Restoring balance to redefine care
By harnessing the power of regulatory T cells, we are developing therapies that aim to reset the immune system rather than just manage symptoms.
Trial in Progress
Clinical Trial for Crohn's Disease
A new investigational cell therapy to address the root causes of Crohn’s disease and help restore balance in the body.
Coming Soon
Clinical Trial for Multiple Sclerosis
A first-in-class therapy in development for MS, engineered to slow disease progression by strengthening immune regulation and protecting neural pathways.
Trial in Progress
Clinical Trial for Hematopoietic Stem Cell Transplant
A first-in-class therapy for the prevention of Graft versus Host Disease (GvHD) following hematopoietic stem cell transplant (HSCT).
Trial in Progress
Clinical Trial for Autoimmune Uveitis (IIT)
A new investigational cell therapy to help address the root causes of autoimmune uveitis and prevent vision loss.
Relentlessly dedicated to improving patient lives
We are pursuing breakthrough innovations in autoimmunity, driven by a world-class team committed to transforming the treatment of devastating diseases.
life at Tr1X
Help us reimagine how autoimmune diseases are treated
We are a team of scientists, doctors, engineers and builders driven by curiosity and compassion.
Join us as we build a new path for patients living with autoimmune and inflammatory conditions.